This category belongs to characters who have high levels of intellect.
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B
- Bane (Post-Crisis)
- Bardock
- Bartholomew Roberts
- Batman (Arkham)
- Batman (DC Animated Universe)
- Batman (DC Extended Universe)
- Batman (Post-Crisis)
- Batman (The LEGO Movie)
- Ben 10,000 (Ultimate Alien)
- Bendu (Star Wars)
- Big Hat Logan
- Bismuth
- Blossom (2016)
- Blue Beetle (Jaime Reyes)
- Blue Diamond
- Bowser
- Brainiac (Post-Crisis)
- Brainstorm
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D
G
H
J
K
L
M
P
R
S
- Sans
- Santana
- Sardonyx
- Scorpion (Mortal Kombat)
- Secret Agent Aliens
- Shadow the Hedgehog
- Sherlock Holmes
- Shinnok
- SixSix
- Son Gohan
- Son Goku (Dragon Ball GT)
- Son Goku (Dragon Ball Super)
- Son Goku (Part I)
- Son Goku (Part II)
- Son Goku (Toei)
- Sonic the Hedgehog
- Spider Mastermind
- Spider-Man (Marvel Animated Universe)
- Spider-Man (Marvel Cinematic Universe)
- Spider-Man (Raimi Trilogy)
- Spider-Man (The Amazing Spider-Man)
- Springtrap
- Starlight Glimmer
- Stormo
- Sub-Zero
- Sun Wukong
- Superman (Post-Crisis)
- Superman (Pre-Crisis)
- Superman (Red Son)
- Superman (Strange Visitor)
- Superman Prime (One Million)
- Swamp Thing